This module takes an in-depth look at normal neurological development and neural plasticity in the paediatric population with particular emphasis on the impact of the subluxation. The case history as a subluxation diagnosis tool is explored. Plagiocephaly is a perfect example of the short and long term effects of subluxation on the skeletal system and also on neurological development. Learning how to manage cases of Plagiocephaly allows us to integrate all the information and concepts we are introduced to in this Module. We finish by covering the clinical management of pain in children.